| Literature link | GPT Summary | Evidence category | Disease type |
|---|---|---|---|
| 28783527 | The study investigates the relationship between circulating microRNAs during early to mid-pregnancy and the risk of developing gestational diabetes mellitus (GDM), considering the influence of pre-pregnancy body mass index (BMI) and fetal sex as potential modifiers. It found significant positive associations between certain miRNAs (miR-155-5p, -21-3p) and GDM, with some miRNAs showing stronger associations in overweight/obese women or those carrying male fetuses. These findings suggest that miRNAs could play a role in the mechanisms behind GDM and help in early identification of at-risk pregnancies. | Risk factor | GDM |
| 31058973 | The study aimed to explore the role of placenta-derived miRNAs in the development of GDM by comparing miRNA expression in EVs from the serum of women who developed GDM and healthy controls during early pregnancy. The researchers found that ten miRNAs, including hsa-miR-122-5p, had significantly higher levels in GDM cases compared to controls, suggesting that these miRNAs could play a role in the pathophysiology of GDM and offer a potential biomarker for early diagnosis. | Risk factor | GDM |
RF's name
hsa-miR-210-3p
RF's type
miRNA