VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
hsa-miR-455-3p This research explores the variation in miRNA profiles within exosomes derived f… Serum Maternal Exosomal GDM(n=19),Normal Glucose Tolerance(n=62)
Western Blotting before 18th gestational weeks Early-Pregnancy Serum Maternal and Placenta-Derived Exosomes miRNAs Vary Based on Pancreatic β-Cell Function in GDM 2024 The Journal of Clinical Endocrinology & Metabolism 38127956 Mechanism
hsa-miR-149-3p This research explores the variation in miRNA profiles within exosomes derived f… Serum Maternal Exosomal GDM(n=19),Normal Glucose Tolerance(n=62)
Western Blotting before 18th gestational weeks Early-Pregnancy Serum Maternal and Placenta-Derived Exosomes miRNAs Vary Based on Pancreatic β-Cell Function in GDM 2024 The Journal of Clinical Endocrinology & Metabolism 38127956 Mechanism
BAFF The study investigates the roles of BAFF and APRIL in predicting the development… Serum GDM(n=10),Normal Glucose Tolerance(n=62)
ELISA;RT-qPCR 6th to 12th gestational weeks Logistic Regression Serum BAFF (B-cell activating factor) and APRIL (a proliferation-inducing ligand) levels in the first trimester may predict the future development of gestational diabetes mellitus 2024 Diabetes & Metabolic Syndrome: Clinical Research & Reviews 38653036 Risk factor
APRIL The study investigates the roles of BAFF and APRIL in predicting the development… Serum GDM(n=10),Normal Glucose Tolerance(n=62)
ELISA;RT-qPCR 6th to 12th gestational weeks Logistic Regression Serum BAFF (B-cell activating factor) and APRIL (a proliferation-inducing ligand) levels in the first trimester may predict the future development of gestational diabetes mellitus 2024 Diabetes & Metabolic Syndrome: Clinical Research & Reviews 38653036 Risk factor
VitB1 The study investigates the relationship between maternal B vitamins (B1, B6, and… Serum GDM(n=121),Normal Glucose Tolerance(n=944)
Electro-Chemiluminescent Assays 8th to 15th gestational weeks Multivariable Logistic Regression;Restricted Cubic Spline (RCS) Regression The Association between Maternal B Vitamins in Early Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study 2022 Nutrients 36501046 Risk factor
VitB6 The study investigates the relationship between maternal B vitamins (B1, B6, and… Serum GDM group (n = 121) and non-GDM group (n = 944)
Electro-Chemiluminescent Assays 8th to 15th gestational weeks Multivariable Logistic Regression;Restricted Cubic Spline (RCS) Regression The Association between Maternal B Vitamins in Early Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study 2022 Nutrients 36501046 Risk factor
FT3 to FT4 ratio This study explored the prospective associations between thyroid markers in earl… Serum GDM(n=298),Normal Glucose Tolerance(n=585)
Chemiluminescent Immunoassays 10.4 ± 2.0 gestational weeks A Prospective Study of Early-pregnancy Thyroid Markers, Lipid Species, and Risk of Gestational Diabetes Mellitus 2022 Journal of Clinical Endocrinology & Metabolism 34453541 Risk factor
ALP This study explored the relationship between early maternal alkaline phosphatase… Serum GDM(n=169),Normal Glucose Tolerance(n=1904);Q1(13.0–38U/L,n=519),Q2 (38–44U/L,n=518),Q3 (44–50U/L,n=517),Q4 (>50U/L,n=519)
Colorimetric method 16±2 gestational weeks Early maternal circulating alkaline phosphatase with subsequent gestational diabetes mellitus and glucose regulation: a prospective cohort study in China 31115769 Endocrine 31115769 Risk factor
ALT This study investigated the relationship between alanine aminotransferase (ALT)… Serum GDM(n=1332),Normal Glucose Tolerance(n=16027)
Enzymatic Methods 4th to 12th gestational weeks Plasma Levels of Alanine Aminotransferase in the First Trimester Identify High Risk Chinese Women for Gestational Diabetes 2016 Scientific Reports 27264612 Risk factor
FT3 This study explored the relationship between thyroid markers and gestational dia… Serum 9.8 ± 1.9, 17.0 ± 4.0 and 32.0 ± 2.8 gestational weeks
Chemiluminescent Microparticle Immunoassay 9.8 ± 1.9, 17.0 ± 4.0 and 32.0 ± 2.8 gestational weeks A longitudinal study of thyroid markers during pregnancy and the risk of gestational diabetes mellitus and post-partum glucose metabolism 2021 Diabetes-metabolism Research And Reviews 33486811 Risk factor