| Literature link | GPT Summary | Evidence category | Disease type |
|---|---|---|---|
| 37873933 | This research aimed to identify and validate key genes in the placenta that could be related to gestational diabetes mellitus (GDM). Two datasets, GSE70493 and PRJNA646212, were analyzed for differentially expressed genes (DEGs), leading to the identification of 20 common DEGs. These genes were then validated in placental tissues from GDM patients and in a cellular model using HTR8/SVneo cells treated with high glucose. The findings indicated changes in gene expression patterns that correlated with GDM, suggesting their potential use as biomarkers for the prevention and management of GDM, as well as for improving pregnancy outcomes and fetal prognosis. | Risk factor | GDM |
RF's name
ITGAX
RF's type
mRNA