Disease's type
GDM
Experimental grouping
GDM(n=578),Normal Glucose Tolerance(n=1697)
GPT's summary
This study assessed the efficacy of first-trimester glycated hemoglobin (HbA1c-FT) in predicting gestational diabetes mellitus (GDM) among Asian Indian women. In a cohort of 2,275 women, those with GDM had a significantly higher mean HbA1c-FT (5.04% vs. 4.9%, p < 0.001). Women with HbA1c-FT levels of 5.2–5.5% and >5.6% had an increased adjusted odds ratio for GDM of 1.627 (p < 0.004) and 2.6 (p < 0.001), respectively, compared to those with HbA1c-FT <5.2%. Although HbA1c-FT was identified as an independent predictor of GDM, its area under the ROC curve (0.606) indicated insufficient sensitivity and specificity for it to serve as a standalone diagnostic test.
RF's name
Hemoglobin A1c
Sample's type
Whole Blood
Gestational weeks
13th to 20th gestational weeks
Experiemental methods
Ion-Exchange High Performance Liquid Chromatography(Ion-Exchange HPLC)
Title
Glycated haemoglobin in the first trimester: A predictor of gestational diabetes mellitus in pregnant Asian Indian women
Evidence's type
Risk factor
Year
2020
Journal
Diabetes Research And Clinical Practice
PMID