| Literature link | GPT Summary | Evidence category | Disease type |
|---|---|---|---|
| 29587878 | The study investigates whether afamin, a vitamin E-binding protein, can serve as an early biomarker for predicting gestational diabetes mellitus (GDM). Afamin's concentration increases during pregnancy and is associated with insulin resistance and metabolic syndrome. Two cohorts were analyzed: one from the first trimester and another from the mid-trimester. The first-trimester cohort included 59 GDM patients and 51 controls, while the mid-trimester cohort included 105 women. Afamin concentrations were significantly higher in GDM patients, especially those requiring insulin treatment (iGDM). The findings suggest that afamin could be a promising early biomarker for GDM, but further research is needed to confirm its predictive value. | Risk factor | GDM |
| 34803906 | This research developed a prediction model for GDM using maternal age, afamin levels during early pregnancy, triglyceride levels, and the platelet-to-lymphocyte ratio. The model demonstrated satisfactory performance with an AUC of 0.748 and a good fit according to the Hosmer-Lemeshow test, suggesting it could be helpful for the early diagnosis and intervention of GDM. | Risk factor | GDM |
RF's name
Afamin
RF's type
protein