Disease's type
GDM
Experimental grouping
GDM=1062,NGDM=4203;p-BMI<18.5（%） NGDM=621 GDM=89 ,18.5–23.9 (%) NGDM=2896 GDM=645 ,24–27.9 (%) NGDM=522 GDM=245,≥28 (%) NGDM=129 GDM=76
GPT's summary
This study evaluated the predictive effects of early pregnancy lipid profiles and fasting glucose on the risk of gestational diabetes mellitus (GDM) in women stratified by prepregnancy body mass index (p-BMI). A retrospective survey in Beijing included 5,265 singleton pregnancies without prepregnancy diabetes. The study identified early pregnancy lipid profiles, such as cholesterol, triglycerides, LDL-C/HDL-C ratio, and TG/HDL-C ratio, along with fasting glucose, as potential markers for GDM prediction. Among these, fasting glucose was found to be the most accurate indicator. The predictive effects and optimal cut-off values for these factors varied by p-BMI, suggesting that p-BMI should be considered in risk assessments for GDM development.
RF's name
Triglyceride to High Density Lipoprotein Cholesterol ratios
Sample's type
Serum
Gestational weeks
before 14th gestational weeks
Experiemental methods
Enzymatic Methods
Title
The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index
Evidence's type
Risk factor
Year
2016
Journal
Journal of Diabetes Research
PMID