Disease's type
GDM
Experimental grouping
GDM(n=25),Normal Glucose Tolerance(n=78)
GPT's summary
This study explored the relationship between altered levels of adipocytokines and inflammatory markers during early pregnancy and the subsequent development of gestational diabetes mellitus (GDM). Samples were collected from high-risk pregnant women, and various biomarkers were measured. After adjusting for several maternal factors, the study found that decreased levels of HMW adiponectin and omentin-1, along with increased levels of IL-6, were significantly associated with the development of GDM. These findings suggest that these biomarkers could improve early risk prediction for GDM, potentially enabling early intervention and better management of the condition.
RF's name
Omentin-1
Sample's type
Fasting venous blood
Gestational weeks
12th to 15th gestational weeks
Experiemental methods
ELISA
Machine learning algorithms
Multivariable Logistic Regression
Title
The association between dysregulated adipocytokines in early pregnancy and development of gestational diabetes
Evidence's type
Risk factor
Year
2017
Journal
Diabetes Research And Clinical Practice
PMID