Disease's type
Inflammatory
GPT's summary
"
Omentin is an adipokine primarily produced by visceral fat tissue and exists in two isoforms, omentin-1 and omentin-2. Omentin-1 is predominantly secreted by the stromal vascular fraction cells of white adipose tissue (WAT), especially in visceral depots such as epicardial adipose tissue. Emerging evidence highlights omentin-1’s critical role in regulating glucose homeostasis, offering potential therapeutic benefits for obesity and diabetes management. Moreover, omentin-1 has been implicated in atheroprotection and anti-inflammatory effects, suggesting its role in cardiovascular health. This review discusses the therapeutic potential of omentin-1 in addressing metabolic disorders, focusing on its regulatory effects on glucose metabolism and cardiovascular protection."
Omentin is an adipokine primarily produced by visceral fat tissue and exists in two isoforms, omentin-1 and omentin-2. Omentin-1 is predominantly secreted by the stromal vascular fraction cells of white adipose tissue (WAT), especially in visceral depots such as epicardial adipose tissue. Emerging evidence highlights omentin-1’s critical role in regulating glucose homeostasis, offering potential therapeutic benefits for obesity and diabetes management. Moreover, omentin-1 has been implicated in atheroprotection and anti-inflammatory effects, suggesting its role in cardiovascular health. This review discusses the therapeutic potential of omentin-1 in addressing metabolic disorders, focusing on its regulatory effects on glucose metabolism and cardiovascular protection."
RF's name
Omentin-1
Title
Omentin: A Key Player in Glucose Homeostasis, Atheroprotection, and Anti-Inflammatory Potential for Cardiovascular Health in Obesity and Diabetes
Evidence's type
Mechanism
Year
2024
Journal
Biomedicines
PMID