Disease's type
GDM
Experimental grouping
GDM(n=90),Normal Glucose Tolerance(n=92)
GPT's summary
The study evaluated several serum biomarkers, including glycosylated fibronectin, for predicting gestational diabetes mellitus (GDM) in the first trimester. Among these, glycosylated fibronectin showed significant independent association with GDM and superior performance in detecting GDM compared to other markers, with an AUC of 0.91. At a threshold of 120 mg/L, it achieved a positive predictive value of 63% and a negative predictive value of 95%.
RF's name
Glycosylated Fibronectin
Sample's type
Serum
Gestational weeks
5th to 13th gestational weeks
Experiemental methods
ELISA
Machine learning algorithms
Logistic regression
Title
Glycosylated fibronectin as a first-trimester biomarker for prediction of gestational diabetes
Evidence's type
Risk factor
Year
2013
Journal
Obstetrics & Gynecology
PMID