Disease's type
GDM
Experimental grouping
GDM(n=4026),Normal Glucose Tolerance(n=9595)
GPT's summary
This retrospective study analyzed the impact of maternal vitamin E concentrations throughout pregnancy on the incidence of gestational diabetes mellitus (GDM) and large-for-gestational-age (LGA) infants. It found that higher than adequate levels of vitamin E, particularly in the second trimester, were associated with an increased risk of both GDM and LGA. Maintaining appropriate vitamin E levels during pregnancy may help prevent these adverse outcomes. Further research is needed to understand the underlying mechanisms.
RF's name
Vitamin E
Sample's type
Serum
Gestational weeks
before 13th gestational weeks
Experiemental methods
High-Performance Liquid Chromatography (HPLC)
Machine learning algorithms
Multivariate Logistic Regression
Title
The Influence of Maternal Vitamin E Concentrations in Different Trimesters on Gestational Diabetes and Large-for-Gestational-Age: A Retrospective Study in China
Evidence's type
Risk factor
Year
2022
Journal
Nutrients
PMID