Disease's type
GDM
Experimental grouping
GDM(n=93),Normal Glucose Tolerance(n=574)
GPT's summary
This study investigates the relationship between maternal fat-soluble antioxidants (vitamins A and E) in early pregnancy and the risk of developing gestational diabetes mellitus (GDM). It found that higher levels of vitamin A in early pregnancy are associated with an increased risk of GDM, while no significant association was found for vitamin E. However, there was a trend suggesting a protective effect of the vitamin E/cholesterol ratio against GDM. Vitamin A shows potential as a biomarker for predicting GDM.
RF's name
Vitamin E
Sample's type
Plasma
Gestational weeks
8th to 10th gestational weeks
Experiemental methods
high-performance liquid chromatography
Machine learning algorithms
Multivariable logistic regression
Title
The association of maternal fat-soluble antioxidants in early pregnancy with gestational diabetes mellitus: a prospective cohort study
Evidence's type
Risk factor
Year
2022
Journal
Nutrition & Diabetes
PMID