Disease's type
GDM
Experimental grouping
GDM(n=45),Normal Glucose Tolerance(n=269)
GPT's summary
This study investigates the relationship between early pregnancy levels of MMP-8 and -9 in GCF and the severity of periodontitis, as well as the risk of developing GDM. The findings indicate that higher concentrations of MMP-8 and -9 in GCF are linked to severe periodontitis and an increased risk of GDM, suggesting potential utility as biomarkers for early detection of GDM.
RF's name
Matrix Metallopeptidase 8
Sample's type
Gingival Crevicular Fluid (GCF)
Gestational weeks
11th to 14th gestational weeks
Experiemental methods
Multiplex Elisa Assays
Title
Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and -9 are associated with the severity of periodontitis and the development of gestational diabetes mellitus
Evidence's type
Risk factor
Year
2020
Journal
Journal of Periodontology
PMID