Disease's type
GDM
Experimental grouping
GDM(n=23),Normal Glucose Tolerance(n=46)
GPT's summary
"The study aimed to explore the role of placenta-derived miRNAs in the development of GDM by comparing miRNA expression in EVs from the serum of women who developed GDM and healthy controls during early pregnancy. The researchers found that ten miRNAs, including hsa-miR-122-5p, had significantly higher levels in GDM cases compared to controls, suggesting that these miRNAs could play a role in the pathophysiology of GDM and offer a potential biomarker for early diagnosis.
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RF's name
hsa-miR-132-3p
Sample's type
Serum Extracellular Vesicles
Gestational weeks
6th to 15th gestational weeks
Experiemental methods
qPCR
Title
miRNA Profiles in Extracellular Vesicles From Serum Early in Pregnancies Complicated by Gestational Diabetes Mellitus
Evidence's type
Risk factor
Year
2019
Journal
Journal of Clinical Endocrinology & Metabolism (J Clin Endocrinol Metab)
PMID