Disease's type
GDM
Experimental grouping
GDM(n=10),Normal Glucose Tolerance(n=10)
GPT's summary
This study used next-generation sequencing to identify differentially expressed miRNAs in maternal plasma during early pregnancy, focusing on those associated with GDM. It found 32 miRNAs that were differentially expressed, with five being validated by qRT-PCR. These miRNAs are linked to insulin resistance and abnormal pregnancies, suggesting their potential as noninvasive biomarkers for early diagnosis of GDM.
RF's name
hsa-miR-20a-5p
Sample's type
Peripheral Blood
Gestational weeks
16th to 19th gestational weeks
Experiemental methods
qRT-PCR
Title
Profiling maternal plasma microRNA expression in early pregnancy to predict gestational diabetes mellitus
Evidence's type
Risk factor
Year
2015
Journal
International Journal of Gynecology and Obstetrics
PMID