Disease's type
GDM
Experimental grouping
GDM(n=200),Normal Glucose Tolerance(n=800)
GPT's summary
This study found that in the GDM group, compared to the control group, the median TNF-α level was significantly increased (1.303 MoM, interquartile range [IQR] 1.151-1.475 vs. 1.0 MoM, IQR 0.940-1.064; p=0.031), while the median Hs-CRP level was not significantly different (1.113 MoM, IQR 0.990-1.250 vs. 1.0 MoM, IQR 0.943-1.060; p=0.084). When predicting GDM, the AUROC for maternal characteristics with TNF-α or Hs-CRP did not significantly differ from the AUROC for maternal characteristics alone (p=0.5055 and p=0.2197, respectively).
RF's name
Tumor Necrosis Factor alpha
Sample's type
Serum
Gestational weeks
11th to 13th gestational weeks
Experiemental methods
Quantikine TNF-α ELISA
Title
First trimester screening for gestational diabetes mellitus by maternal factors and markers of inflammation
Evidence's type
Risk factor
Year
2022
Journal
Metabolism
PMID