Disease's type
GDM
Experimental grouping
GDM(n=121),Normal Glucose Tolerance(n=944)
GPT's summary
The study investigates the relationship between maternal B vitamins (B1, B6, and B12) measured in early pregnancy and the incidence of GDM later in pregnancy. It found that elevated levels of vitamin B1 and B6 in early pregnancy are linked to a higher risk of developing GDM, whereas adequate levels of vitamin B12 are associated with a reduced risk. Nonlinear relationships between serum vitamin B6 and B12 and GDM risk were identified using statistical modeling.
RF's name
Vitamin B1
Sample's type
Serum
Gestational weeks
8th to 15th gestational weeks
Experiemental methods
Electro-Chemiluminescent Assays
Machine learning algorithms
Multivariable Logistic Regression；Restricted Cubic Spline (RCS) Regression
Title
The Association between Maternal B Vitamins in Early Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study
Evidence's type
Risk factor
Year
2022
Journal
Nutrients
PMID