Disease's type
GDM
Experimental grouping
GDM(n=10),Normal Glucose Tolerance(n=62)
GPT's summary
The study investigates the roles of BAFF and APRIL in predicting the development of GDM. It finds that elevated serum BAFF and reduced serum APRIL levels in the first trimester are strongly associated with the later onset of GDM, indicating their potential as early biomarkers for this condition.
RF's name
B-cell activating factor
Sample's type
Serum
Gestational weeks
6th to 12th gestational weeks
Experiemental methods
ELISAï¼›RT-qPCR
Machine learning algorithms
Logistic Regression
Title
Serum BAFF (B-cell activating factor) and APRIL (a proliferation-inducing ligand) levels in the first trimester may predict the future development of gestational diabetes mellitus
Evidence's type
Risk factor
Year
2024
Journal
Diabetes & Metabolic Syndrome: Clinical Research & Reviews
PMID