VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
hsa-miR-29b-3p "The study aimed to explore the role of placenta-derived miRNAs in the deve… Serum Extracellular Vesicles GDM(n=23),Normal Glucose Tolerance(n=46)
qPCR 6th to 15th gestational weeks miRNA Profiles in Extracellular Vesicles From Serum Early in Pregnancies Complicated by Gestational Diabetes Mellitus 2019 Journal of Clinical Endocrinology & Metabolism (J Clin Endocrinol Metab) 31058973 Risk factor
S100A9 This research aimed to explore the differences in the exosomal proteome of 24-ho… Exosome Protein of 24 hour Urine GDM(n=8),Normal Glucose Tolerance(n=10)
Western blotting At 20th gestational weeks Negative binomial generalized linear models Proteomic analyses of Urine Exosomes reveal New Biomarkers of Diabetes in Pregnancy 2016 Madridge Journal of Diabetes 31448371 Risk factor
APTT This research evaluated the predictive value of maternal coagulation function an… Plasma GDM(n=142),Normal Glucose Tolerance(n=442)
Coagulation Method 10th to 13th gestational weeks Logistic Regression Application Value of Predictive Model Based on Maternal Coagulation Function and Glycolipid Metabolism Indicators in Early Diagnosis of Gestational Diabetes Mellitus 2022 Frontiers in Public Health 35387184 Risk factor
hsa-miR-342-3p "The study aimed to explore the role of placenta-derived miRNAs in the deve… Serum Extracellular Vesicles GDM(n=23),Normal Glucose Tolerance(n=46)
qPCR 6th to 15th gestational weeks miRNA Profiles in Extracellular Vesicles From Serum Early in Pregnancies Complicated by Gestational Diabetes Mellitus 2019 Journal of Clinical Endocrinology & Metabolism (J Clin Endocrinol Metab) 31058973 Risk factor
S100A8 Calprotectin, a novel marker of obesity, has recently gained attention for its p… Increased levels of calprotectin in obesity are related to macrophage content: impact on inflammation and effect of weight loss 2011 Mol Med 21738950 Mechanism
MMP8 This study investigates the relationship between early pregnancy levels of MMP-8… Gingival Crevicular Fluid (GCF) GDM(n=45),Normal Glucose Tolerance(n=269)
Multiplex Elisa Assays 11th to 14th gestational weeks Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and -9 are associated with the severity of periodontitis and the development of gestational diabetes mellitus 2020 Journal of Periodontology 32789908 Risk factor
MMP8 The study explores the potential of cell-free DNA and RNA from maternal plasma a… Maternal plasma and cord blood plasma GDM(n=13),Normal Glucose Tolerance(n=99)
qRT-PCR During the first trimester of pregnancy Expectation-Maximization Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes 2021 Epigenetics 33045922 Risk factor
S100A8 The study explores the potential of cell-free DNA and RNA from maternal plasma a… Maternal plasma and cord blood plasma GDM(n=13),Normal Glucose Tolerance(n=99)
qRT-PCR During the first trimester of pregnancy Expectation-Maximization Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes 2021 Epigenetics 33045922 Risk factor
GPNMB Metabolism in mammals is regulated by the complex interplay between different or… Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance 2019 Nat Metab 32694855 Mechanism
ITGAX This research aimed to identify and validate key genes in the placenta that coul… Placental Tissue and HTR8/SVneo Cell Line. GDM(n=14),Normal Glucose Tolerance(n=14)
RT-qPCR At the time of cesarean delivery Analysis, validation, and discussion of key genes in placenta of patients with gestational diabetes mellitus 2023 Experimental Biology and Medicine 37873933 Risk factor