VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
UA This cohort study investigated the association between serum uric acid (UA) leve… Serum GDM(n=960),Normal Glucose Tolerance(n=73649)
Enzymatic methods before 12th gestational weeks Logistic Regression Serum uric acid in early pregnancy and risk of gestational diabetes mellitus: A cohort study of 85,609 pregnant women 2022 Diabetes & Metabolism Journal 34666165 Risk factor
HbA1c This study investigated the optimal HbA1c threshold for detecting undiagnosed di… Whole Blood HbA1c < 5.2%:GDM(n=568),Normal Glucose Tolerance(n=3863),5.9%< HbA1c <6.4%, GDM(n=124),Normal Glucose Tolerance(n=69),HbA1c ≥ 6.5%, GDM(n=16),Normal Glucose Tolerance(n=2)
Ion-Exchange High Performance Liquid Chromatography(Ion-Exchange HPLC) before 12th gestational weeks An early pregnancy HbA1c ≥5.9% (41 mmol/mol) is optimal for detecting diabetes and identifies women at increased risk of adverse pregnancy outcomes 2014 Diabetes Care 25190675 Risk factor
HbA1c This study aimed to develop a predictive model for early identification of gesta… Whole Blood GDM(n=264),Normal Glucose Tolerance(n=528)
Urbidimetric Inhibition Immunoassay 14th to 17th gestational weeks Logistic Regression Early prediction of gestational diabetes: a practical model combining clinical and biochemical markers 2016 Clinical Chemistry And Laboratory Medicine 26351946 Risk factor
HbA1c This study assessed whether an early hemoglobin A1c (HbA1c) value of 5.7–6.4% co… Whole Blood HbA1c<5.7%,GDM(n=14),Normal Glucose Tolerance(n=251); HbA1c 5.7-6.4%=55,GDM(n=5),Normal Glucose Tolerance(n=27)
Ion-Exchange High Performance Liquid Chromatography(Ion-Exchange HPLC) before 20th gestational weeks Use of hemoglobin A1c as an early predictor of gestational diabetes mellitus 2014 American Journal of Obstetrics And Gynecology 24912095 Risk factor
HbA1c This study evaluated the potential of hemoglobin A1c (HbA1c) as an early screeni… Whole Blood HbA1c<5.7%, GDM(n=67),Normal Glucose Tolerance(n=130); HbA1c≥5.7%, GDM(n=17),Normal Glucose Tolerance(n=6)
Ion-Exchange High Performance Liquid Chromatography(Ion-Exchange HPLC) before 12th gestational weeks HbA1c during early pregnancy reflects beta-cell dysfunction in women developing GDM 2020 Bmj Open Diabetes Research & Care 33132213 Risk factor
HbA1c This study assessed the efficacy of first-trimester glycated hemoglobin (HbA1c-F… Whole Blood GDM(n=578),Normal Glucose Tolerance(n=1697)
Ion-Exchange High Performance Liquid Chromatography(Ion-Exchange HPLC) 13th to 20th gestational weeks Glycated haemoglobin in the first trimester: A predictor of gestational diabetes mellitus in pregnant Asian Indian women 2020 Diabetes Research And Clinical Practice 31794807 Risk factor
TG This study developed and validated an early risk prediction model for gestationa… Serum Randomly divided into a modeling cohort (GDM=1225,NGDM=2975) and validation cohort (GDM=519,NGDM=1281)
Glycerol-3-phosphate Oxidase-PAP Method 8th to 12th gestational weeks Logistic Regression Establishment of gestational diabetes risk prediction model and clinical verification 2024 Journal of Endocrinological Investigation 38085430 Risk factor
TG This study investigated whether early pregnancy maternal plasma lipid levels are… Plasma GDM(n = 47),Normal Glucose Tolerance(n = 804)
Glycerol-3-phosphate Oxidase-PAP Method before 13th gestational weeks,on average A Generalized Linear Interactive Modeling System Early pregnancy lipid concentrations and the risk of gestational diabetes mellitus 2005 Diabetes Research And Clinical Practice 16188575 Risk factor
TG This study investigated the combined effects of free thyroxine (FT4) and triglyc… Serum GDM(n=4819),Normal Glucose Tolerance(n=35337)
Glycerol-3-phosphate Oxidase-PAP Method 9th to 13th gestational weeks Association of maternal triglyceride responses to thyroid function in early pregnancy with gestational diabetes mellitus 2022 Frontiers in Endocrinology 36518243 Mechanism
TG Insulin resistance in skeletal muscle, a key feature of obesity-linked type 2 di… Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes 2008 Nat Rev Mol Cell Biol 18401346 Mechanism