VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
sPRR This study investigated the association between plasma soluble (pro)renin recept… Plasma GDM group (n = 44) and non-GDM group (n = 672)
 ELISA before 14th gestational weeks Logistic Regression Prediction of gestational diabetes mellitus by soluble (pro)renin receptor during the first trimester 2013 Journal of Clinical Endocrinology & Metabolism 23720787 Risk factor
IGF-I to IGFBP-3 ratio This prospective case-control study examined the role of insulin-like growth fac… Plasma GDM(n=107),Normal Glucose Tolerance(n=214)
 ELISA 10th to 14th gestational weeks Insulin-Like Growth Factor Axis and Gestational Diabetes Mellitus: A Longitudinal Study in a Multiracial Cohort 2016 Diabetes 27468747 Risk factor
Nes-1 This study investigated the potential roles of serum nesfatin-1 and vaspin level… Serum GDM(n=153),Normal Glucose Tolerance(n=84)
 ELISA before 10th gestational weeks Nesfatin-1 and Vaspin as Potential Novel Biomarkers for the Prediction and Early Diagnosis of Gestational Diabetes Mellitus 2019 International Journal of Molecular Science 30621139 Risk factor
Nes-1 This study investigates the role of nesfatin-1, a peptide derived from nucleobin… Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance 2012 Diabetes 22688332 Mechanism
ANGPTL8 This study explores the potential of using angiopoietin-like protein 8 (ANGPTL8)… Plasma GDM(n=88),Normal Glucose Tolerance(n=386)
 ELISA 12th to 16th gestational weeks Multivariable Logistic Regression Angiopoietin-like protein 8 in early pregnancy improves the prediction of gestational diabetes 2018 Diabetologia 29167926 Risk factor
ANGPTL8 Angiopoietin-like protein 8 (ANGPTL8), a secreted protein primarily expressed in… Emerging insights into the roles of ANGPTL8 beyond glucose and lipid metabolism 2023 Front Physiol 38107478 Mechanism
LDL-C to HDL-C ratio The research evaluated how early pregnancy lipid levels and fasting glucose can… Plasma Participants were divided into four groups based on pre-pregnancy BMI: underweight (p-BMI < 18.5 kg/m2), normal weight (18.5 ≤ p-BMI < 24 kg/m2), overweight (24 ≤ p-BMI < 28 kg/m2), and obese (p-BMI ≥ 28 kg/m2).
 Two Point End Method before 14th gestational weeks Logistic Regression The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index 2016 Journal of Diabetes Research 26981541 Risk factor
ANGPTL2 This prospective, nested case-control study investigated the association between… Serum GDM(n=89),Normal Glucose Tolerance(n=177)
 ELISA 11th to 13th gestational weeks Association between Maternal Serum Concentrations of Angiopoietin-like Protein 2 in Early Pregnancy and Subsequent Risk of Gestational Diabetes Mellitus 2016 Chinese Medical Journal 27647189 Risk factor
OMNT1 This study explored the relationship between altered levels of adipocytokines an… Fasting venous blood GDM(n=25),Normal Glucose Tolerance(n=78)
 ELISA 12th to 15th gestational weeks Multivariable Logistic Regression The association between dysregulated adipocytokines in early pregnancy and development of gestational diabetes 2017 Diabetes Research And Clinical Practice 28806491 Risk factor
AMT This prospective study explored the associations between inflammatory blood cell… Whole Blood GDM group (n = 455) and non-GDM group (n = 5909)
 Impedance Method before 15th gestational weeks Blood Cell Parameters From Early to Middle Pregnancy and Risk of Gestational Diabetes Mellitus 2023 Journal of Clinical Endocrinology & Metabolism 37279929 Risk factor