VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
TG to HDL-C ratio This study aimed to develop a simplified screening model to identify pregnant Ch… Serum GDM(n=272),Normal Glucose Tolerance(n=1017)
 Enzymatic Methods 6th to 12th gestational weeks logistic regression A Simplified Screening Model to Predict the Risk of Gestational Diabetes Mellitus in Pregnant Chinese Women 2023 Diabetes Therapy 37843770 Risk factor
TG to HDL-C ratio This study evaluated the predictive effects of early pregnancy lipid profiles an… Serum GDM=1062,NGDM=4203;p-BMI<18.5（%） NGDM=621 GDM=89 ,18.5–23.9 (%) NGDM=2896 GDM=645 ,24–27.9 (%) NGDM=522 GDM=245,≥28 (%) NGDM=129 GDM=76
 Enzymatic Methods before 14th gestational weeks The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index 2016 Journal of Diabetes Research 26981541 Risk factor
RBP4 Retinol-binding protein 4 (RBP4), an adipocyte-derived factor, plays a pivotal r… Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes 2005 Nature 16034410 Mechanism
ALP This study aimed to investigate the relationship between maternal liver biomarke… Serum GDM(n=1668),Normal Glucose Tolerance(n=7480)(ALP,Q1:15-43,Q2:44-50,Q3:51-57,Q4:58-139)
 Colorimetric Method 8th to 14th gestational weeks The associations of maternal liver biomarkers in early pregnancy with the risk of gestational diabetes mellitus: a prospective cohort study and Mendelian randomization analysis 2024 Frontiers in Endocrinology 38836232 Risk factor
ALT This study investigated the relationship between alanine aminotransferase (ALT)… Serum GDM(n=1332),Normal Glucose Tolerance(n=16027)
 Enzymatic Methods 4th to 12th gestational weeks Plasma Levels of Alanine Aminotransferase in the First Trimester Identify High Risk Chinese Women for Gestational Diabetes 2016 Scientific Reports 27264612 Risk factor
FABP4 Lipids play a fundamental role in cellular processes and disease pathogenesis, y… Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets 2008 Nat Rev Drug Discov 18511927 Mechanism
FABP4 This study examined the association between first-trimester plasma fatty acid-bi… Plasma GDM(n=135),Normal Glucose Tolerance(n=1015)
 ELISA First prenatal visit Logistic Regression,Quartile Analysis First-Trimester Serum Fatty Acid-Binding Protein 4 and Subsequent Gestational Diabetes Mellitus 2017 Obstetrics And Gynecology 29016489 Risk factor
FABP4 Fatty acid-binding protein 4 (FABP4), predominantly expressed in adipocytes, mon… A New Insight into Fatty Acid Binding Protein 4 Mechanisms and Therapeutic Implications in Obesity-Associated Diseases: A Mini Review 2024 Mol Nutr Food Res 38593305 Mechanism
FABP4 This study aimed to evaluate the diagnostic potential of fatty acid-binding prot… Serum GDM(n=46),Normal Glucose Tolerance(n=55)
 ELISA 23th to 30th gestational weeks Plasma fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus 2016 Acta Diabetologica 27147422 Risk factor
FABP4 This study investigated the role of fatty acid-binding protein 4 (FABP4) in insu… Plasma GDM(n=135),Normal Glucose Tolerance(n=135)
 ELISA before 14th gestational weeks & 25th to 28th gestational weeks Risk of Gestational Diabetes Mellitus in relation to Plasma Concentrations of Fatty Acid-Binding Protein 4: A Nested Case-Control Study in China 2021 Journal of Diabetes Research 34368366 Risk factor