| FT4 |
This study aimed to investigate the combined effect of serum ferritin (SF) conce… |
Serum |
SF(Lowest)fT4(Lowest), N=91(1.39%);SF(Highest)fT4(Lowest), N=65(0.99%);SF(Normal)fT4(Lowest), N=204(3.12%);SF(Lowest)fT4(Normal), N=1465(22.39%);SF(Highest)fT4(Normal), N=1581(24.17%);SF(Normal)fT4(Normal), N=3136(47.94%)
|
CLIA |
first antenatal visit |
Do free thyroxine levels influence the relationship between maternal serum ferritin and gestational diabetes mellitus in early pregnancy? |
2019 |
Diabetes Research And Clinical Practice |
30935929 |
Risk factor |
| Ins |
Insulin receptor substrate-1 (IRS-1) is a key mediator of insulin and insulin-li… |
Serum |
|
|
|
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 |
1994 |
Nature |
7969452 |
Mechanism |
| Ins |
Cardiovascular disease (CVD) has long been the leading cause of death globally,… |
Serum |
|
|
|
Association between insulin resistance and the development of cardiovascular disease |
2018 |
Cardiovasc Diabetol |
30170598 |
Mechanism |
| Ins |
Ceramide, a lipid mediator produced in response to stress, plays a critical role… |
Serum |
|
|
|
Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism |
2003 |
Mol Cell Biol |
14560023 |
Mechanism |
| Ins |
Insulin resistance is a hallmark of type 2 diabetes and is observed in various c… |
Serum |
|
|
|
Reactive oxygen species have a causal role in multiple forms of insulin resistance |
2006 |
Nature |
16612386 |
Mechanism |
| Ins |
This study investigates the role of protein kinase C (PKC) activation in modulat… |
Serum |
|
|
|
Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612 |
1997 |
Biochemistry |
9335553 |
Mechanism |
| Folate |
This study found that low vitamin B12 and high folate levels in early pregnancy… |
Serum |
4746 pregnant women, NICE-GDM(n=538),IADPSG-GDM(n=633)
|
Electro-Chemiluminescent Immunoassay |
before 12.5 gestational weeks |
Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes: a prospective UK cohort study (PRiDE study) |
2021 |
Diabetologia |
34296321 |
Risk factor |
| LDL-C |
This study found that early pregnancy lipid profiles are associated with pregnan… |
Serum |
GDM(n=1053),Normal Glucose Tolerance(n=4165)
|
Two Point End Method |
4th to 13th gestational weeks |
The associations between early pregnancy lipid profiles and pregnancy outcomes |
2017 |
Journal of Perinatology |
27787507 |
Risk factor |
| Lep |
This study investigated the role of first-trimester leptin, resistin, and visfat… |
Serum |
GDM(n=70),Normal Glucose Tolerance(n=70)
|
ELISA |
11th to 13th gestational weeks |
Leptin, resistin and visfatin as useful predictors of gestational diabetes mellitus |
2019 |
Lipids in Health And Disease |
31836012 |
Risk factor |
| Lep |
Nutritional deprivation suppresses immune function, and the discovery of the obe… |
|
|
|
|
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression |
1998 |
Nature |
9732873 |
Mechanism |
