VALIDATION
| ID | GPT's Summary | Sample's type | Experimental grouping | Experiemental methods | Gestational weeks | Machine learning algorithms | Article's title | Year | Journal | PMID | Evidence type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Alb | This research identified eight significant pre- and early-pregnancy factors link… | Serum | GDM(n=49611),Normal Glucose Tolerance(n=137821) |
Bromocresol Green Method | 8th to 12th gestational weeks | Logistic Regression | Association of pre- and early-pregnancy factors with the risk for gestational diabetes mellitus in a large Chinese population | 2021 | Scientific Reports | 33795771 | Risk factor |
| T3 | This study investigated the associations between T3 and T3/fT4 with glucose meta… | Serum | GDM(n=335),Normal Glucose Tolerance(n=2387) |
Electrochemiluminescence | before 12th gestational weeks | Time-Specific Generalized Estimating Equation | The role of triiodothyronine (T3) and T3/free thyroxine (fT4) in glucose metabolism during pregnancy: the Ma'anshan birth cohort study | 2021 | Endocrine Connections | 34077392 | Risk factor |
| VitE | This retrospective study analyzed the impact of maternal vitamin E concentration… | Serum | GDM(n=4026),Normal Glucose Tolerance(n=9595) |
High-Performance Liquid Chromatography (HPLC) | before 13th gestational weeks | Multivariate Logistic Regression | The Influence of Maternal Vitamin E Concentrations in Different Trimesters on Gestational Diabetes and Large-for-Gestational-Age: A Retrospective Study in China | 2022 | Nutrients | 35458191 | Risk factor |
| Nes-1 | This study investigates the role of nesfatin-1, a peptide derived from nucleobin… | Nesfatin-1 action in the brain increases insulin sensitivity through Akt/AMPK/TORC2 pathway in diet-induced insulin resistance | 2012 | Diabetes | 22688332 | Mechanism | |||||
| Nes-1 | This study investigated the potential roles of serum nesfatin-1 and vaspin level… | Serum | GDM(n=153),Normal Glucose Tolerance(n=84) |
ELISA | before 10th gestational weeks | Nesfatin-1 and Vaspin as Potential Novel Biomarkers for the Prediction and Early Diagnosis of Gestational Diabetes Mellitus | 2019 | International Journal of Molecular Science | 30621139 | Risk factor | |
| OMNT1 | This study explored the relationship between altered levels of adipocytokines an… | Fasting venous blood | GDM(n=25),Normal Glucose Tolerance(n=78) |
ELISA | 12th to 15th gestational weeks | Multivariable Logistic Regression | The association between dysregulated adipocytokines in early pregnancy and development of gestational diabetes | 2017 | Diabetes Research And Clinical Practice | 28806491 | Risk factor |
| OMNT1 | " Omentin is an adipokine primarily produced by visceral fat tissue… |
Omentin: A Key Player in Glucose Homeostasis, Atheroprotection, and Anti-Inflammatory Potential for Cardiovascular Health in Obesity and Diabetes | 2024 | Biomedicines | 38397886 | Mechanism | |||||
| Hct | This study assessed the diagnostic accuracy of multiple complete blood count (CB… | Whole Blood | GDM group (n = 49) and non-GDM group (n = 551) |
Impedance Method | before 12th gestational weeks | Multivariate Longitudinal Random-Effects | Diagnostic accuracy of first and early second trimester multiple biomarkers for prediction of gestational diabetes mellitus: a multivariate longitudinal approach | 2022 | Bmc Pregnancy And Childbirth | 34983441 | Risk factor |
| OMNT1 | This study identifies a novel visceral fat-specific adipokine, named omentin, wh… | Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action | 2006 | Am J Physiol Endocrinol Metab | 16531507 | Mechanism | |||||
| AST | This study aimed to investigate the relationship between maternal liver biomarke… | Serum | GDM(n=1668),Normal Glucose Tolerance(n=7480)(ALP,Q1:15-43,Q2:44-50,Q3:51-57,Q4:58-139) |
Enzymatic Methods | 8th to 14th gestational weeks | The associations of maternal liver biomarkers in early pregnancy with the risk of gestational diabetes mellitus: a prospective cohort study and Mendelian randomization analysis | 2024 | Frontiers in Endocrinology | 38836232 | Risk factor |