VALIDATION

ID GPT's Summary Sample's type Experimental grouping Experiemental methods Gestational weeks Machine learning algorithms Article's title Year Journal PMID Evidence type
FT3 This study investigated the relationship between first-trimester thyroid hormone… Serum GDM(n=1177),Normal Glucose Tolerance(n=4718),assigned to quintile groups according serum FT3 levels
 Chemiluminescent Immunoassay before 12th gestational weeks Effects of thyroid hormones modify the association between pre-pregnancy obesity and GDM: evidence from a mediation analysis 2024 Frontiers in Endocrinology 39345886 Risk factor
FT3 This study explored the association between free T3 (fT3), the fT3/fT4 ratio, an… Serum GDM(n=107),Normal Glucose Tolerance(n=214)
 Electrochemiluminescence Immunoassay, ECLIA 10th to 14th, 15th to 26th, 24th to 31th, and 33th to 39th gestational weeks A Longitudinal Study of Thyroid Markers Across Pregnancy and the Risk of Gestational Diabetes 2018 Journal of Clinical Endocrinology & Metabolism 29889229 Risk factor
FT4 This study investigated the relationship between thyroid hormone levels in early… Serum GDM(n=3697),Normal Glucose Tolerance(n=23816)
 Chemiluminescent Microparticle Immunoassays 9th to 13th gestational weeks Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus 2016 Journal of Clinical Endocrinology & Metabolism 27583471 Risk factor
C-pep Serum Competitive Chemiluminescent Immunoassay 10th to 14th gestational weeks & 15th to 20th gestational weeks Maternal fasting serum C-peptide concentrations in the first and second trimesters and subsequent risk of gestational diabetes mellitus: A nested case-control study among Chinese women 2024 Diabetes Research And Clinical Practice 38266822 Risk factor
ALT This study aimed to develop a predictive model for gestational diabetes mellitus… Serum (training, internal validation=7:3)GDM=137,NGDM=128;(external validation)133 pregnant women
 Enzymatic Methods before 12th gestational weeks Logistic Regression Construction and validation of a line chart for gestational diabetes mellitus based on clinical indicators 2024 Lipids in Health And Disease 39462412 Risk factor
ALT This study investigated the relationship between liver function biomarkers in ea… Serum GDM(n=1688),Normal Glucose Tolerance(n=7480)(ALT,Q1:1-10U/L,Q2:11-13U/L,Q3:14-19U/L,Q4:20-87U/L)
 Enzymatic Methods 8th to 14th gestational weeks The associations of maternal liver biomarkers in early pregnancy with the risk of gestational diabetes mellitus: a prospective cohort study and Mendelian randomization analysis 2024 Frontiers in Endocrinology 38836232 Risk factor
Res This study investigated the roles of adipokines (leptin, resistin, and visfatin)… Serum GDM(n=70),Normal Glucose Tolerance(n=70)
 ELISA 11th to 13th gestational weeks Leptin, resistin and visfatin as useful predictors of gestational diabetes mellitus 2019 Lipids in Health And Disease 31836012 Risk factor
ANT Lung cancer remains the leading cause of cancer-related mortality worldwide, wit… Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth 2010 Nature Medicine 20081861 Mechanism
Ins This study investigated whether elevated serum insulin levels in early pregnancy… Serum GDM(n=43),Normal Glucose Tolerance(n=28)
CLIA before 16th gestational weeks Prediction of gestational diabetes mellitus in a high-risk group by insulin measurement in early pregnancy 2005 Diabetic Medicine 16176208 Risk factor
FT4 This study investigated the relationship between thyroid function and the risk o… Serum GDM(n=444),Normal Glucose Tolerance(n=1767),assigned to quintile groups according serum FT4 levels
 CLIA first antenatal visit Association between thyroid function and risk of gestational diabetes mellitus in assisted pregnancies: A retrospective cohort study 2021 Diabetes Research And Clinical Practice 33310125 Risk factor